抗HA广谱抗体
HA具有独特作用,广泛用于抗流感抗体的研究。通过WB和ELISA对HA抗原进行识别。结果表明,兔单抗86001-RM01和11053-R004分别是甲型和乙型流感的广谱抗体。
Number | Antigens | ELISA Assay | WB Assay | ELISA Assay | WB Assay | Antigen Subtype | Antigen Strain | Vaccine Strain |
86001-RM01 | 11053-R004 | |||||||
1 | 40719-V08H | +++ | +++ | - | - | H1N1 | A/Brisbane/02/2018 | 2019-2020 |
2 | 11055-V08H | +++ | +++ | - | - | A/California/04/2009 | - | |
3 | 11085-V08B | +++ | +++ | - | - | A/California/07/2009 | 2016-2017, 2015-2016 | |
4 | 40717-V08H | +++ | +++ | - | - | A/Guangdong-Maonan/SWL1536/2019 | 2020-2021 | |
5 | 40567-V08H1 | +++ | +++ | - | - | A/Michigan/45/2015 | 2018-2019, 2017-2018 | |
6 | 11684-V08H | +++ | +++ | - | - | A/Puerto Rico/8/1934 | - | |
7 | 40787-V08H | +++ | +++ | - | - | (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) | 2021-2022 | |
8 | 11056-V08H | +++ | +++ | - | - | H3N2 | A/Brisbane/10/2007 | - |
9 | 40789-V08H | +++ | +++ | - | - | A/Cambodia/e0826360/2020 | 2021-2022 | |
10 | 40721-V08H | +++ | +++ | + | - | A/Hong Kong/2671/2019 | 2020-2021 | |
11 | 40765-V08H | +++ | +++ | - | - | A/Hong Kong/45/2019 | 2020-2021 | |
12 | 40555-V08B | +++ | +++ | - | - | A/Hong Kong/4801/2014 | 2017-2018, 2016-2017 | |
13 | 40720-V08H | +++ | +++ | - | - | A/Kansas/14/2017 | 2019-2020 | |
14 | 40580-V08H | +++ | +++ | - | - | A/Singapore/INFIMH-16-0019/2016 | 2018-2019 | |
15 | 40497-V08B | +++ | +++ | - | - | A/Switzerland/9715293/2013 | 2015-2016 | |
16 | 40016-V08B | - | - | +++ | +++ | Influenza B | B/Brisbane/60/2008 | 2017-2018, 2016-2017, 2015-2016 |
17 | 40581-V08H | - | - | +++ | +++ | B/Colorado/06/2017 | 2019-2020, 2018-2019 | |
18 | 11053-V08H | - | - | +++ | +++ | B/Florida/4/2006 | - | |
19 | 40498-V08B | - | - | +++ | +++ | B/PHUKET/3073/2013 | 2021-2022, 2020-2021, 2019-2020, 2018-2019, 2017-2018, 2016-2017, 2015-2016 | |
20 | 40722-V08H | - | - | +++ | +++ | |||
B/Washington/02/2019 | 2021-2022, 2020-2021 |
-: No Effect; +: Medium/Minimal Effect; +++: Strong Effect