B.S. in Biology, July 1937, Zhejiang University, Hangzhou, China.

Ph.D in Genetics, September 1949, Institute of Animal Genetics, Edinburgh, Scotland, U.K.

Professional Experience:

1937-1946: Assistant, Lecturer, Associate Professor, Department of Biology,

Zhejiang University, Meitan, Guizhou, China ( with Prof. S. Pai ).

1946-1949: PhD Thesis: “Cytochemical studies on the embryonic and post-

embryonic development of Drosophila melanogaster” ( Supervisor:

Prof. C.H.Waddington).

1950: Professor, Department of Biology, Zhejiang University, Hangzhou,

China

1950-1978: Research Professor. Institute of Experimental Biology, Academia

Sinica, Shanghai, China.

1964-1983: Deputy Director, Institute of Experimental Biology, which in 1978

was renamed as the Shanghai Institute of Cell Biology, Chinese

Academy of Sciences.

1984- Research Professor, Shanghai Institute of Cell Biology, CAS.

Research Interest:

(1) Embryonic stem cells, induced differentiation etc.

(2) Cancer cell biology

Honors:

1980: Elected as a Member, Division of Biology, Chinese Academy of

Sciences

1982: Organizer, “International Workshop-Symposium of Chemical

Carcinogenesis: Chemical, Mctabolic and Biological Aspects”. Under the

auspices of the Chinese Academy of Sciences and the National

foundation for Cancer Research, USA. October,1982, Shanghai, China.

1984: Organizer, Satellite Symposium of the Third International Congress on

Cell Biology in Tokyo Japan on “Organization and function of genomes

particular emphasis on gene regulation”. September, 1984,

Shanghai, China.

1983-86,1995-99: President, Chinese Society for Cell Biology

1988-90: President, Asian-Pacific Organization for Cell Biology (APOCB)

1990: Organizer, First Congress of Asian-Pacific Organization for Cell Biology, November, 1990, Shanghai, China.

1990: Editor-in-Chief, Cell Research, a journal reporting on basic research in the fields of animal and plant cell biology published in English.

Selected publications:

1942: Yao T, S Pai. Heteropycnosis and chromatin diminution in Cosmocerca sp. Science Record 1 (1-2) 197-202.

1945: Yao T. Studies on the organizer problem in Pelmatohydra oligactis. I, II, III. J Exp Biol 21(3-4) 147-60.

1950: Yao T. Cytochemical studies on the embryonic development of Drosophila melanogester. II. Alkaline and acid phosphatases. Quart J Microscop Sci 91(part 1) 79-88.

1956: Yao T, CY Cheng. Properties and changes of phosphatase activity during Drosophila metamorphosis. Acta Biol Exp Sinica 5(1) 123-36.

1977: Shi WK, Lu YL, Ye M, Z Yao. Membrane-associated embryonic antigen on human hepatocellular carninoma cells Acta Zool Sinica 23(4) 337-44.

1980a: Tsung HC, Shi WK, Z Yao. In situ localization of tumor associated antigen in human primary hepatoma cells. Acta Biol Exp Sinica 13(3) 317-29.

1980b: Yao Z. Aspects of research studies on liver carcinoma. In: Paul A Marks ed, Cancer Research in the People's Republic of China and the United States of America. Grune and Stratton Inc PP 145-60.

1982: Shi WK, Chen ZK, Z Yao. Differential response of F9 mouse teratocarcinoma cells to retinoic acid. Acta Biol Exp Sinica 15(1) 341-55.

1983: Tsung HC, Z Yao. Preliminary study of the characteristics of two cloned F9 teratocarcinoma cells. Ditto 16(1) 93-105.

1984: Tsung HC, Z Yao. The induced differentiation of the cloned B7-2 embryonal carcinoma cells by hexamethylene bisacetamide (HMBA). Ditto 17(3) 309-21.

1985a: Hsu WM, Song QB, Z Yao. Hybrids between F9 "nullipotent" teratocarcinoma cells and rat thymus cells produce differentiated cells. Ditto 18(2) 177-87.

1985b: Yao Z, HC Tsung. Influences of in vivo microenvironment on the differentiation of cloned B7-2 embryonal carcinoma cells. Ditto 18(2) 239-49.

1985c: Xie H, Z Yao et al. Two mouse hybridoma secreting monoclonal antibodies against human liver carcinoma and their antibody specificity. Ditto 18(2) 239-49.

1987: Tsung HC, Z Yao. Some biological characteristics and karyotype analysis of a mouse embryonic stem cell line ES-8501 cells. Dotto 20(2) 237-51.

1991a: Xu J, Tsung HC, Z Yao. Induced differentiation of mouse embryonic stem cells by retinoic acid and dibutyryl cyclic adenosine monophosphate. Ditto 24(2)353-67.

1991b: Fuhrer JP, Xie H, Murphy MJ, Ye JN, Z Yao. Characterization of a membrane-associated glycoprotein (gp 43) on human hepatocallula carcinoma by a monoclonal antibody. Cancer Res 51(4) 2158-63.

1993: Zeng ZC et al. Radioimmunotherapy for unresectable hepatocellular carcinoma using 131-Hepama-1 mAb: preliminary results. J Cancer Res Clin Oncol 119:257-9.

1995: Tsung HC, Xia SH, Xu LX, Li XL, Shi WK, Z Yao. Expression of exogenous porcine transforming growth beta-1 gene in ES cells and its effect on their differentiation in vitro. Acta Biol Exp Sinica 28(2) 173-89.

1996a: Tsung HC and Z Yao. The mechanism of vasculogenesis: The critical role of transforming growth factor-b1 in the formation of vessel-like structures during the differentiation in vitro of murine embryonic stem cells. Ditto 29(3)273-285.

1996b: Tsung HC, Xu J, Xu LX, Li XL, Shi WK, Z Yao. Can overexpression of TGF-b1 gene change the sex ratio in transgenic mice? Cell Res 6(1) 55-63.

1998: Du ZW, Tsung HC, Z Yao. Expression of retinoic acid receptor g gene in ES cells and its effect on their differentiation and apoptosis. Acta Biol Exp Sinica 31(2) 155-69.