EDITOR

Tom Mulligan, MSc
Tel: +44 1403 220755
Email: tom@sp2.uk.com


SALES DIRECTOR
Jaymin Amin, BEng
Tel: +44 1403 220754
Email: jaymin@sp2.uk.com


EUROPEAN SALES MANAGER
Chris Shaw
Tel: +44 1606 833891
Email: chris@sp2.uk.com


PUBLISHER
Mark Harrington, BSc
Tel: +44 1403 220753
Email: mark@sp2.uk.com


PUBLISHING CONSULTANT
Brian Cooper, MA, CEng


CONTRIBUTOR
Dr Enrico Polastro


CHINA OFFICE
Beijing Oriental Foreland Consultants
Co, Ltd
1904, Blding.5, District 3
Tian Tong Yuan
Changping District
Beijing 102218
China.
Tel: +86 10 84823421
Fax: +86 10 84846103
Email: info@fair114.com
Contact: Jane Eyre


SUBSCRIPTIONS
Sarah Johnson
Tel: +44 1403 220750


EXHIBITION CO-ORDINATOR
Valerie Shilling
Email: valerie@sp2.uk.com


WEBSITE DESIGN
Siric Communications
Tel: +44 1403 210168
Email: info@siric.com


WEBSITES
www.sp2.uk.com
www.biofine.uk.com
www.biofineusa.com


Annual subscription

EDITORTom Mulligan, MSc
Tel: +44 1403 220755
Email: tom@sp2.uk.com
SALES DIRECTOR
Jaymin Amin, BEng
Tel: +44 1403 220754
Email: jaymin@sp2.uk.com
EUROPEAN SALES MANAGER
Chris Shaw
Tel: +44 1606 833891
Email: chris@sp2.uk.com
PUBLISHER

ISSN 1476-184X

　

Companies and organisations
featured in articles in this issue
BioCatalytics, Inc36
CSS, Chemical SynthesisServices   16
DOTTIKON EXCLUSIVE SYNTHESIS                                   14
FluorousTechnologies,Inc                28
GeneBio SA / Genedata AG            32
LibraGen                                        38
Scientific Update /
Select Conferences                         24
INFORMEX                                    40
Syrrris Ltd                                      20

　

　

　

　

　

　

　
C O N T E N T S

Editor ¨s page

 4

News & Events

 6

Executive Spotlight
Markus Blocher, CEO of DOTTIKON EXCLUSIVE SYNTHESIS, outlines the company¨s strategy in the custom hazardous chemistry business sector

 14

Integrating technologies for
complete chemical synthesis
CSS has expanded its offerings in drug development through the addition of new technologies and the formation of new alliances

 16

Automated micro flow chemistry
for process development
An automated micro flow system completes chemical synthesis and analysis in one unit, allowing rapid reaction optimisation and scale-up

 20

Cover feature: Molecules that matter: case
studies in medchem
Corinne Kay of Med-Simple reviews the medicinal chemistry conference organised by Scientific Update and Select Conferences as part of this year¨s
BioFine event

 24

Cover feature: Applying fluorous technology in
medicinal chemistry
Fluorous28-31.pdf Technologies, Inc has greatly increased its product offerings and expanded into new application areas in drug discovery.

 28

Computational platforms for large-scale
proteomics applications
Geneva Bioinformatics SA and Genedata AG are collaborating on high-throughput solutions for analysing proteomics data for drug discovery

 32

Broadening the scope of biocatalysis
There are many different chemistries that can be carried out using biocatalysis, ranging from resolutions to reductions, oxidations, aminations and condensation reactions. This article reviews recent progress in the field

 36

Using biodiversity to identify new biocatalysts
By focusing on untapped biodiversity, LibraGen has developed a platform of prorietary technologies to identify, validate and produce high-added-value enzymes and molecules for a range of applications including pharmaceutical and fine chemical synthesis

 38

Event preview: INFORMEX 2006
INFORMEX, SOCMA¨s custom chemicals show takes place in Orlando, Florida from February 14-17, 2006. We present some of the highlights of the exhibition

 40

Out of Hours: Orlando
Orlando plays host to INFORMEX in February. We review some of the attractions of the city and surrounding areas                           

42