《Nature》专题：被忽视的疾病 -《Nature》|专题|被忽视的疾病-生物通

生物通报道：热带疾病给10多亿人类带来了无尽的痛苦，但是至今为止有效的治疗方法并不多，而且虽然进行了许多科学研究，但是许多具
有治疗潜力的科学创新并不能从实验室里走出来。

《Nature》杂志最新副刊以“Neglected diseases”为题，提示大家关注这一领域，也审视了促进有效医药发展，以及将这些方法传递给最需要的人的处理办法。

Neglected Diseases p157

David O'Connell

doi:10.1038/449157a

Lost in translation p158

The culture of academia needs to change if scientists are to bridge the gap between research and the development of drugs and vaccines for neglected diseases in the developing world, says Declan Butler.

Declan Butler

doi:10.1038/449158a

Full Text | PDF (541K)

A tough transition p160

What is holding back biotechnology in the developing world? Peter A. Singer and his colleagues listen to those on the ground.

Peter A. Singer, Kathryn Berndtson, C. Shawn Tracy, Emma R. M. Cohen, Hassan Masum, James V. Lavery & Abdallah S. Daar

doi:10.1038/449160a

Full Text | PDF (818K) | Supplementary information

The path to new medicines p164

Governments must help accelerate the development of drugs needed to treat infectious diseases in the developing world, say Bénédicte Callan and Iain Gillespie.

Bénédicte Callan & Iain Gillespie

doi:10.1038/449164a

Full Text | PDF (336K)

Mission possible p166

One billion people worldwide suffer from tropical diseases. Andrew L. Hopkins, Michael J. Witty and Solomon Nwaka explain how drug-discovery networks might be scaled up to address the lack of treatments cost-effectively.

Andrew L. Hopkins, Michael J. Witty & Solomon Nwaka

doi:10.1038/449166a

Full Text | PDF (674K)

A prescription for drug delivery p170

Improvements in basic infrastructure are the key to saving millions of lives each year, say Julian Lob-Levyt and his colleagues.

Rebecca Affolder, Ivone Rizzo, Craig Burgess, Abdallah Bchir & Julian Lob-Levyt

doi:10.1038/449170a

Full Text | PDF (736K)

Patent sense p174

Protecting intellectual property saves lives in the developing world, argues Paul Herrling.

Paul Herrling

doi:10.1038/449174a

Full Text | PDF (451K)

At what price? p176

Differential pricing could make global medicines affordable in developing countries. But drugs for diseases that have no market in the developed world will require additional subsidies, says Patricia M. Danzon.

Patricia M. Danzon

doi:10.1038/449176a

Full Text | PDF (570K)

The road to recovery p180

Brazil urgently needs to improve infrastructure for generating pharmaceuticals to alleviate the plight of its poor and marginalized populations, say Carlos M. Morel et al.

Carlos M. Morel, José R. Carvalheiro, Carmen N. P. Romero, Eduardo A. Costa & Paulo M. Buss

doi:10.1038/449180a

Full Text | PDF (413K)